Three-dimensional single particle tracking using 4π self-interference of temporally phase-shifted fluorescence

Leanne Maurice; Alberto Bilenca

doi:10.1038/s41377-023-01085-7

Light: Science & Applications (Mar 2023)

Three-dimensional single particle tracking using 4π self-interference of temporally phase-shifted fluorescence

Leanne Maurice,
Alberto Bilenca

Affiliations

Leanne Maurice: Biomedical Engineering Department, Ben-Gurion University of the Negev
Alberto Bilenca: Biomedical Engineering Department, Ben-Gurion University of the Negev

DOI: https://doi.org/10.1038/s41377-023-01085-7
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 10

Abstract

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Conventional widefield excitation and temporal phase-shift fluorescence interference in a basic 4π-interferometer enable video rate, multiple particle tracking with isotropic, 3D precision over large volumes in cells and deep in soft materials.

Published in Light: Science & Applications

ISSN: 2047-7538 (Online)
Publisher: Nature Publishing Group
Country of publisher: United Kingdom
LCC subjects: Technology: Engineering (General). Civil engineering (General): Applied optics. Photonics; Science: Physics: Optics. Light
Website: https://www.nature.com/lsa/

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