Vascular Health and Risk Management (Nov 2021)
Heart Rate Variability and Cardiovascular Fitness: What We Know so Far
Abstract
Hugo Celso Dutra Souza, Stella Vieira Philbois, Ana Catarine Veiga, Bruno Augusto Aguilar Department of Health Science, Ribeirão Preto Medical School of University of São Paulo, São Paulo, BrazilCorrespondence: Hugo Celso Dutra SouzaRibeirão Preto Medical School, University of São Paulo, Laboratory of Exercise Physiology and Cardiovascular Physiotherapy, Av. Bandeirantes, 3900 - Vila Monte Alegre - Ribeirão Preto, São Paulo, 14049-900, BrazilTel +55163315-4416Fax +55163315-4413Email [email protected]: Fluctuation analysis in intervals between heartbeats provides important indices related to autonomic modulation of heart rate variability (HRV). These indices are considered predictors of morbidity and mortality as they are frequently altered in patients with chronic degenerative diseases, especially in those with cardiovascular and metabolic diseases. Similarly, a reduction in HRV is common with aging. In all cases, cardiovascular fitness is often reduced to below the predicted values. In turn, increases in cardiovascular fitness through regular physical exercise, especially aerobic exercise, represent an important therapeutic tool capable of promoting positive adjustments in cardiac autonomic modulation. These adjustments are characterized by reduced sympathetic modulatory influence and/or increased vagal modulatory influence on the heart, increasing the HRV. Therefore, several methodological tools have been used to assess the degree of impairment of autonomic modulation and the therapeutic effects of physical exercise. In contrast, establishment of strict protocols in experimental design is a main challenge in establishing HRV analysis as a robust parameter for evaluating cardiovascular homeostasis. Thus, this review aimed to contribute to the understanding of autonomic modulation of HRV and its relationship with cardiovascular fitness, highlighting the advances made thus far, the applicability of analysis tools, and the confounding factors observed frequently.Keywords: heart rate variability, cardiovascular fitness
