mSphere of Influence: Learning from Nature—Antibody Profiles Important for Protection of Young Infants

Abstract

ABSTRACT Esther Ndungo works in the field of maternal-infant immunity against enteric pathogens. In this mSphere of Influence article, she reflects on how the paper “Fc glycan-mediated regulation of placental antibody transfer” by Jennewein et al. (M. F. Jennewein, I. Goldfarb, S. Dolatshahi, C. Cosgrove, et al., Cell 178:202–215.e14, 2019, https://doi.org/10.1016/j.cell.2019.05.044) impressed upon her the value of thinking “outside the box” and looking to nature to guide her research.

Keywords

• antibody profiles
• enteric pathogens
• maternal-infant immunity
• systems serology