Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium
Camila Spereta Bertanha,
Ana Helena Januário,
Tavane Aparecida Alvarenga,
Letícia Pereira Pimenta,
Márcio Luis Andrade e Silva,
Wilson Roberto Cunha,
Patrícia Mendonça Pauletti
Affiliations
Camila Spereta Bertanha
Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil
Ana Helena Januário
Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil
Tavane Aparecida Alvarenga
Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil
Letícia Pereira Pimenta
Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil
Márcio Luis Andrade e Silva
Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil
Wilson Roberto Cunha
Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil
Patrícia Mendonça Pauletti
Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil
Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones. This review discusses the isolation, structural elucidation, and biological activities of quinones, hydroquinones, rossinones, longithorones, longithorols, floresolides, scabellones, conicaquinones, aplidinones, thiaplidiaquinones, and conithiaquinones. A compilation of the 13C-NMR spectral data of these compounds is also presented.
