Frontiers in Microbiology (Oct 2022)

The regulation of antiviral activity of interferon epsilon

  • Fu-Rong Zhao,
  • Fu-Rong Zhao,
  • Wei Wang,
  • Qin Zheng,
  • Yan-Ge Zhang,
  • Jianming Chen

DOI
https://doi.org/10.3389/fmicb.2022.1006481
Journal volume & issue
Vol. 13

Abstract

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Interferon epsilon (IFN-ε) is a type I IFN. Some biological properties has been identified in many species, such as antiproliferative, anti-tumor, and antiviral effects, of IFN-ε, which are much weaker than those of IFN-α, have also been revealed. It has been shown to play a role in mucosal immunity and bacterial infection and in the prevention of certain sexually transmitted diseases, such as human immunodeficiency virus (HIV). This paper reviews the known activity of IFN-ε, particularly in some viruses. In general, this review provides a better understanding of effective IFN-ε treatment in the future.

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