Copper-catalyzed synthesis of diarylamines using p-toluene sulfonamides and benzhydrol derivatives under homogeneous borrowing hydrogen conditions

Abstract

Diarylamines were synthesized using p-toluene sulfonamides with benzhydrol derivatives in the presence of a copper/bisphosphine complex by Borrowing Hydrogen (BH) mechanism, yielding ${<}98\%$ under clean and mild reaction conditions. The use of readily available and cost-effective copper salts, short reaction times, high yield and reaction rates are highlighted.

Keywords

• Diaryl amine
• Benzhydrol
• sulfonamides
• Copper salt
• Bisphosphine ligands
• Borrowing Hydrogen (BH) mechanism