RUDN Journal of Medicine (Dec 2009)

The studying of connection of molecular-genetic markers of interlakines with the clinical current chronic glomerulonephritis

  • E V Kalmykova,
  • I S Polyakova,
  • K I Proschaev,
  • V G Nesterov,
  • V S Vaschilin,
  • M I Churnosov

Journal volume & issue
Vol. 0, no. 4
pp. 619 – 620

Abstract

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The present research is devoted revealing of interrelations of genetic markers interleukines with clinical signs chronic glomerulonephritis. It is established that a marker of development of mixed type chronic glomerulonephritis at a disease aggravation are genotypes 4R/4R a gene of the antagonist of a receptor interleukin 1 and -592AA, -592AS gene IL-10. The positive association of genotypes 2R/5R, 4R/5R IL-1Ra with type chronic glomerulonephritis in a disease current is revealed.

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