Nature Communications (Apr 2016)

Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection

  • Lamba Omar Sangaré,
  • Tchilabalo Dilezitoko Alayi,
  • Benoit Westermann,
  • Agnes Hovasse,
  • Fabien Sindikubwabo,
  • Isabelle Callebaut,
  • Elisabeth Werkmeister,
  • Frank Lafont,
  • Christian Slomianny,
  • Mohamed-Ali Hakimi,
  • Alain Van Dorsselaer,
  • Christine Schaeffer-Reiss,
  • Stanislas Tomavo

DOI
https://doi.org/10.1038/ncomms11191
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 14

Abstract

Read online

The retromer complex is a multi-protein component of the endosomal protein sorting machinery. Here, Sangaré et al. identify unique features in the retromer complex of the parasite Toxoplasma gondii, and show that it is crucial for the biogenesis of secretory organelles in this pathogen.