International Journal of Women's Health (Apr 2024)
Survival Status and Predictors Among Women with Advanced Stage of Cervical Cancer
Abstract
Roza Teshome,1 Irene Yang,2 Edom Woldetsadik,3 Eshetu Girma,4 Melinda Higgins,2 Jessica Wells2 1Department of Midwifery, School of Nursing & Midwifery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 2Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA; 3Department of Oncology, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 4Department of Preventive Medicine, School of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaCorrespondence: Roza Teshome, Tel +251-911028610, Email [email protected]: Cervical cancer is one of the leading causes of cancer death in women, even though it is a preventable disease. Most deaths occur in low- and middle-income countries. In addition to early detection and receipt of standard treatments, survivorship is an important component of high quality of care across the cancer continuum.Objective: To assess the survival status of advanced-stage cervical cancer patients after cancer treatment has started.Methods and Materials: A one-year prospective cohort study was employed to assess the survival status of women with advanced stages of cervical cancer. A total of 180 cervical cancer patients were recruited, and the study was conducted from January 10, 2022, to September 20, 2023. Data entry and analysis were done in the SPSS 29 version. Descriptive statistics were used to examine participant characteristics. The Kaplan-Meier procedure and log rank test were used to estimate the duration of survival. Bivariate and multivariate Cox regression analyses were computed for predictor variables with survival status.Results: Patients receiving cancer treatment at FIGO stages IVA and IVB had survived by 56% and 24%, respectively, whereas patients receiving treatment at stages IIB and IIIA had survived by 100%. The estimated mean survival time at one-year follow-up was 5.706 months (95% CI: 3.785– 7.627) for patients with FIGO stage IVB, but 11.537 months (95% CI: 11.199– 11.887) for those with stages II and III (P < 0.001). Women over 60 years old had a 1.5-fold higher risk of death than those under 60 (HR: 1.482, P = 0.040).Conclusion: The one-year cumulative survival rate among advanced-stage cervical cancer patients was 77%. Major factors associated with survival were age, cancer stage, the presence of anemia, and waiting time for treatment.Keywords: survival status, advanced stage, cervical cancer, tikur anbessa specialized hospital, Ethiopia
