Emerging Infectious Diseases (Oct 1996)

Rapid Increase of Resistance to Erythromycin and Clindamycin in Streptococcus pyogenes in Italy, 1993-1995

  • Giuseppe Cornaglia,
  • Marco Ligozzi,
  • Annarita Mazzariol,
  • Myriam Valentini,
  • Graziella Orefici,
  • Roberta Fontana

DOI
https://doi.org/10.3201/eid0204.960410
Journal volume & issue
Vol. 2, no. 4
pp. 339 – 342

Abstract

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A survey of antibiotic resistance in Streptococcus pyogenes in Italy showed a sharp increase in erythromycin resistance. In 1993, the incidence of erythromycin-resistant strains was on average 5.1%, with marked variations by geographic area. Two years later, the incidence of these strains had registered a 1.5- to roughly 20-fold increase, with a mean value of 25.9%, exceeding 40% in three centers out of 13 and 30% in another four. For all the strains studied, normal levels of susceptibility to penicillin were reported.

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