DISTURBANCES IN PROTEIN C SYSTEM IN PATIENTS SUFFERING FROM PERIODONTITIS

Abstract

The present research is focused on defining the role of protein С system in the process of blood coagulation and fibrinolysis in patients suffering from different forms ofperiodontitis. The beginning of specific course of treatment in patients with chronic periodontitis there have been diagnosed disturbances in protein С system, the latter being the reason for blood coagulation disorders, such as: the decrease of protein С activity, the decrease of active factor Va resistance, the increase ofplasminogen reserve, the decrease of total antithrombin blood activity, antithrombin III activity including. The degree of changes in protein С system depends on the severity degree of chronic periodontitis: the more severe disease is the more severe disorders itcauses in protein С system. The most evident symptoms of depression of indices in protein С system were observed in patients with quick-progressive periodontitis. The decrease of protein С activity is caused by its consumption in the process of intravascular blood coagulation is characteristic periodontitis.

Keywords

• blood coagulation
• fibrinolysis
• periodontitis
• protein C