Nature Communications (Sep 2018)

Olfactory receptor OR2AT4 regulates human hair growth

  • Jérémy Chéret,
  • Marta Bertolini,
  • Leslie Ponce,
  • Janin Lehmann,
  • Teresa Tsai,
  • Majid Alam,
  • Hanns Hatt,
  • Ralf Paus

DOI
https://doi.org/10.1038/s41467-018-05973-0
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 12

Abstract

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Increasing evidence suggest that olfactory receptors can carry additional functions besides olfaction. Here, Chéret et al. show that stimulation of the olfactory receptor ORT2A4 by the odorant Sandalore® stimulates growth of human scalp hair follicles ex vivo, suggesting the use of ORT2A4-targeting odorants as hair growth-promoting agents.