Pharmaceuticals (Nov 2021)

The Fellowship of Privileged Scaffolds—One Structure to Inhibit Them All

  • Marcin Skoreński,
  • Marcin Sieńczyk

DOI
https://doi.org/10.3390/ph14111164
Journal volume & issue
Vol. 14, no. 11
p. 1164

Abstract

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Over the past few years, the application of privileged structure has emerged as a powerful approach to the discovery of new biologically active molecules. Privileged structures are molecular scaffolds with binding properties to the range of different biological targets. Moreover, privileged structures typically exhibit good drug-like properties, thus assuring more drug-like properties of modified compound. Our main objective is to discuss the privileged structures used for the development of antiviral agents.

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