Emerging Infectious Diseases (Apr 2024)

Drug-Resistant Tuberculosis, Georgia, Kazakhstan, Kyrgyzstan, Moldova, and Ukraine, 2017–2022

  • Victor Naestholt Dahl,
  • Tetiana Butova,
  • Alex Rosenthal,
  • Alina Grinev,
  • Andrei Gabrielian,
  • Sergo Vashakidze,
  • Natalia Shubladze,
  • Bekzat Toxanbayeva,
  • Lyailya Chingissova,
  • Valeriu Crudu,
  • Dumitru Chesov,
  • Gulmira Kalmambetova,
  • Gulbarchyn Saparova,
  • Christian Morberg Wejse,
  • Dmytro Butov

DOI
https://doi.org/10.3201/eid3004.231732
Journal volume & issue
Vol. 30, no. 4
pp. 831 – 833

Abstract

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In 2021, the World Health Organization recommended new extensively drug-resistant (XDR) and pre-XDR tuberculosis (TB) definitions. In a recent cohort of TB patients in Eastern Europe, we show that XDR TB as currently defined is associated with exceptionally poor treatment outcomes, considerably worse than for the former definition (31% vs. 54% treatment success).

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