Frontiers in Neurology (Jan 2018)

Diffusion Weighted/Tensor Imaging, Functional MRI and Perfusion Weighted Imaging in Glioblastoma—Foundations and Future

  • Gayle R. Salama,
  • Linda A. Heier,
  • Praneil Patel,
  • Rohan Ramakrishna,
  • Rajiv Magge,
  • Apostolos John Tsiouris

DOI
https://doi.org/10.3389/fneur.2017.00660
Journal volume & issue
Vol. 8

Abstract

Read online

In this article, we review the basics of diffusion tensor imaging and functional MRI, their current utility in preoperative neurosurgical mapping, and their limitations. We also discuss potential future applications, including implementation of resting state functional MRI. We then discuss perfusion and diffusion-weighted imaging and their application in advanced neuro-oncologic practice. We explain how these modalities can be helpful in guiding surgical biopsies and differentiating recurrent tumor from treatment related changes.

Keywords