Development of 89Zr Labelled Radiopharmaceuticals

Abstract

Positron emission tomography (PET) is the most advanced molecular imaging technology with the advantage of high sensitivity and quantity analysis. Molecule probe is the key factor for PET. 89Zr is a novel imaging nuclide and suitable for labeling macromolecular bioactive substances such as antibody due to its favorably long half-life and energy. This review outlined the recent development of the production of 89Zr, labeling methods and application of 89Zr labelled radiopharmaceuticals.