Research progress in the relationship between obesity and psoriasis

Abstract

Obesity is a major public health problem worldwide, which is linked to the development of chronic inflammation and its related complications, such as psoriasis, type 2 diabetes, hyperlipidemia, atherosclerosis, etc. Obesity and psoriasis can be influenced by multiple factors, such as dietary habits, immune factors, microbiota and environmental factors, but the specific mechanisms are not yet clear. The link between obesity and psoriasis is mainly mediated by fat factors in obese and psoriatic patients, which can activate pro-inflammatory factors, thereby exacerbating psoriasis symptoms. Obesity is one of the important risk factors for psoriatic patients. And compared to normal weight individuals, overweight or obesity can worsen psoriasis. This paper reviews the possible connections between obesity and psoriasis from multiple aspects, including epidemiology, anthropometric indicators, microbiota, diet, pro-inflammatory factors and treatment.

Keywords

• obesity
• psoriasis
• anthropometric indicators
• microbial community
• diet
• pro-inflammatory factors
• treatment