Nature Communications (Jun 2022)

Transition-metal-free synthesis of pyrimidines from lignin β-O-4 segments via a one-pot multi-component reaction

  • Bo Zhang,
  • Tenglong Guo,
  • Zhewei Li,
  • Fritz E. Kühn,
  • Ming Lei,
  • Zongbao K. Zhao,
  • Jianliang Xiao,
  • Jian Zhang,
  • Dezhu Xu,
  • Tao Zhang,
  • Changzhi Li

DOI
https://doi.org/10.1038/s41467-022-30815-5
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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Lignin depolymerization to make heterocyclic aromatic compounds is of great importance to expanding the product portfolio derived from biomass, but it is also particularly challenging. In this work, the authors report pyrimidine synthesis from lignin β-O-4 model compounds via a one-pot multicomponent cascade reaction.