Nature Communications (Jun 2022)
Transition-metal-free synthesis of pyrimidines from lignin β-O-4 segments via a one-pot multi-component reaction
Abstract
Lignin depolymerization to make heterocyclic aromatic compounds is of great importance to expanding the product portfolio derived from biomass, but it is also particularly challenging. In this work, the authors report pyrimidine synthesis from lignin β-O-4 model compounds via a one-pot multicomponent cascade reaction.