Restoration of breathing after opioid overdose and spinal cord injury using temporal interference stimulation

Michael D. Sunshine; Antonino M. Cassarà; Esra Neufeld; Nir Grossman; Thomas H. Mareci; Kevin J. Otto; Edward S. Boyden; David D. Fuller

doi:10.1038/s42003-020-01604-x

Communications Biology (Jan 2021)

Restoration of breathing after opioid overdose and spinal cord injury using temporal interference stimulation

Michael D. Sunshine,
Antonino M. Cassarà,
Esra Neufeld,
Nir Grossman,
Thomas H. Mareci,
Kevin J. Otto,
Edward S. Boyden,
David D. Fuller

Affiliations

Michael D. Sunshine: Rehabilitation Science PhD Program, University of Florida
Antonino M. Cassarà: Foundation for Research on Information Technologies in Society (IT’IS)
Esra Neufeld: Foundation for Research on Information Technologies in Society (IT’IS)
Nir Grossman: Division of Brain Sciences, Imperial College London
Thomas H. Mareci: Department of Biochemistry and Molecular Biology, University of Florida
Kevin J. Otto: J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida
Edward S. Boyden: Departments of Brain and Cognitive Sciences, Media Arts and Sciences, and Biological Engineering, McGovern and Koch Institutes, MIT
David D. Fuller: Department of Physical Therapy, University of Florida

DOI: https://doi.org/10.1038/s42003-020-01604-x
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 15

Abstract

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Sunshine et al use a combination of rat models and in silico modeling to show that temporal interference stimulation can prevent fatal apneas after opioid overdose, and can activate the diaphragm after spinal cord injury. This potentially paves the way for an alternative and minimally invasive treatment

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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