Protocol and statistical analysis plan for the PREventing cardiovascular collaPse with Administration of fluid REsuscitation during Induction and Intubation (PREPARE II) randomised clinical trial

• Shekhar Ghamande,
• Bruno Pereira,
• Christopher J Lindsell,
• Victor E Ortega,
• Aaron M Joffe,
• Heath D White,
• Muhammad Ali,
• David R Janz,
• Kevin M Dischert,
• Emily Adams,
• James M Dargin,
• A M Joffe,
• Akram Khan,
• Simanta Dutta,
• Joanne M Wozniak,
• Susan Stempek,
• Olivia F Krol,
• Brian E Driver,
• Joseph M Brewer,
• Stephen P Peters,
• Rita N Bakhru,
• Scott Bauer,
• Christina R Bellinger,
• Amanda M Brown,
• Blair Brown,
• Jerri Brown,
• Caitlin Bumgarner,
• Wendy Butcher,
• Megan Caudle,
• Arjun B Chatterjee,
• David J Chodos,
• Gerardo Corcino,
• Nathan S Cutler,
• Travis L Dotson,
• Daniel C Files,
• Jonathan L Forbes,
• Katherine A Gershner,
• Shannon Ginty,
• Kiadrick R Hood,
• April Hazelwood,
• Katherine Hendricks,
• Kelly Jacobus,
• Jonathan T Jaffe,
• Stacy Kay,
• Chad A Kloefkorn,
• Jennifer Krall,
• Margo T Lannan,
• Cornelia Lane,
• Cynthia Lanning,
• Jessica Lyons,
• William I Mariencheck,
• Chad R Marion,
• Matthew A Maslonka,
• Sara McClintock,
• Nathaniel M Meier,
• Matthew C Miles,
• Peter J Miller,
• Sophia Mitchell,
• Wendy C Moore,
• Katherine Moss,
• Andrew M Namen,
• Dustin L Norton,
• Stella B Ogake,
• Jill A Ohar,
• Jessica A Palakshappa,
• Rodolfo M Pascual,
• Sandi Pascual,
• Aaron Pickens,
• Adam R Schertz,
• Matt Strong,
• Alexander O Sy,
• Braghadheeswar Thyagarajan,
• Amy Townsend,
• Russell Worthen,
• Michael Wlodarski,
• Charles Yarbrough,
• Caroline York,
• James Dargin,
• Joanne Wozniak,
• Christopher Adler,
• Ahmed Agameya,
• Michael Colancecco,
• Daniel Fitelson,
• Joshua Giaccotto,
• Gena Han,
• Louise Kane,
• Ezra Miller,
• Timothy Noland,
• Jaqueline Price,
• Joseph Plourde,
• Fraser Mackay,
• Laura Mahoney,
• Avignat Patel,
• Michael Plourde,
• Zena Saadeh,
• Sara Shadchehr,
• Sandeep Somalaraju,
• Eleanor Summerhill,
• Ryan Webster,
• Jordan Winnicki,
• Ekaterina Yavarovich,
• D Sheylan,
• Alejandro C Arroliga,
• Tasnim Lat,
• Stephanie Nonas,
• Milad K Jouzestani,
• Raya Adi,
• Chandani Anandkat,
• Hanae Benchbani,
• Matthew G Drake,
• Makrina N Kamel,
• Ramanpreet Randhawa,
• Jessica L Tsui

Affiliations

Shekhar Ghamande

Division of Pulmonary, Critical Care & Sleep Medicine, Baylor Scott and White Central Texas, Temple, Texas, USA

Bruno Pereira

2 DRCI Biostatistical department, University Hospital, Clermont-Ferrand, France

Christopher J Lindsell

5 Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA

Victor E Ortega

Internal Medicine, Wake Forest Health Sciences, Winston-Salem, North Carolina, USA

Aaron M Joffe

Department of Anesthesiology and Pain Medicine, Harborview Medical Center, Seattle, Washington, USA

Heath D White

Baylor Scott and White Central Texas, Temple, Texas, USA

Muhammad Ali

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA

David R Janz

2 School of Medicine, Section of Pulmonary/Critical Care & Allergy/Immunology, Louisiana State University, New Orleans, Louisiana, USA

Kevin M Dischert

4 Department of Anesthesiology and Pain Medicinex, University of Washington, Seattle, Washington, USA

Emily Adams

Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK

James M Dargin

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Lahey Hospital and Medical Center, Burlington, Massachusetts, USA

A M Joffe

Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington, USA

Akram Khan

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University School of Medicine, Portland, Oregon, USA

Simanta Dutta

Department of Medicine, Section of Pulmonary, Critical Care, Allergy and Immunologic Disease, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA

Joanne M Wozniak

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Lahey Hospital and Medical Center, Burlington, Massachusetts, USA

Susan Stempek

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Lahey Hospital and Medical Center, Burlington, Massachusetts, USA

Olivia F Krol

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University School of Medicine, Portland, Oregon, USA

Brian E Driver

Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota, USA

Joseph M Brewer

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA

Stephen P Peters

Wake Forest School of Medicine, Winston-Salem, North Carolina, USA

Rita N Bakhru

Scott Bauer

Christina R Bellinger

Amanda M Brown

Blair Brown

Jerri Brown

Caitlin Bumgarner

Wendy Butcher

Megan Caudle

Arjun B Chatterjee

David J Chodos

Gerardo Corcino

Nathan S Cutler

Travis L Dotson

Daniel C Files

Jonathan L Forbes

Katherine A Gershner

Shannon Ginty

Department of Respiratory Therapy, Mount Sinai Hospital, Toronto, Canada

Kiadrick R Hood

April Hazelwood

Katherine Hendricks

Kelly Jacobus

Jonathan T Jaffe

Stacy Kay

Chad A Kloefkorn

Jennifer Krall

Margo T Lannan

Cornelia Lane

Cynthia Lanning

Jessica Lyons

William I Mariencheck

Chad R Marion

Matthew A Maslonka

Sara McClintock

Nathaniel M Meier

Matthew C Miles

Peter J Miller

Sophia Mitchell

Wendy C Moore

1 Department of Internal Medicine, Pulmonary Section, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA

Katherine Moss

Andrew M Namen

Dustin L Norton

Stella B Ogake

Jill A Ohar

Jessica A Palakshappa

Rodolfo M Pascual

Sandi Pascual

Aaron Pickens

Adam R Schertz

Matt Strong

Alexander O Sy

Braghadheeswar Thyagarajan

Amy Townsend

Russell Worthen

Michael Wlodarski

Charles Yarbrough

Caroline York

James Dargin

Joanne Wozniak

Christopher Adler

Ahmed Agameya

Michael Colancecco

Daniel Fitelson

Joshua Giaccotto

Gena Han

Louise Kane

Ezra Miller

Timothy Noland

Jaqueline Price

Joseph Plourde

Fraser Mackay

Laura Mahoney

Avignat Patel

Michael Plourde

Zena Saadeh

Sara Shadchehr

Sandeep Somalaraju

Eleanor Summerhill

Ryan Webster

Jordan Winnicki

Ekaterina Yavarovich

D Sheylan

Alejandro C Arroliga

Tasnim Lat

Stephanie Nonas

Milad K Jouzestani

Raya Adi

Chandani Anandkat

Hanae Benchbani

Matthew G Drake

Makrina N Kamel

Ramanpreet Randhawa

Jessica L Tsui