Aplastic crisis caused by parvovirus B19 in an adult patient with sickle-cell disease

Abstract

We describe a case of aplastic crisis caused by parvovirus B19 in an adult sickle-cell patient presenting with paleness, tiredness, fainting and dyspnea. The absence of reticulocytes lead to the diagnosis. Anti-B19 IgM and IgG were detected. Reticulocytopenia in patients with hereditary hemolytic anemia suggests B19 infection.

Keywords

• Human parvovirus B19
• Sickle-cell disease
• Transient aplastic crisis
• Reticulocytopenia