Uji Daya Hambat Perasan Air Kunyit (Curcuma domestica Val.) sebagai Antibakteri terhadap Pertumbuhan Bakteri Escherichia coli

Abstract

Diarrhea cases in Indonesia were 270/1000 population or 7,265,013 cases occurred at all ages with a mortality rate (CFR) of 4.76% in 2018. Treatment of diarrhea can be done by giving antibiotics such as Cefotaxime, Ciprofloxacin, Gentamicin, Ampicillin, Metronidazole, Co-trioxide, Ceftriaxone, and Erythromycin. However, inappropriate use of antibiotics can lead to bacterial resistance. Turmeric is a medicinal plant that contains curcumin and essential oils that can inhibit the growth of bacteria. There are 24 essential oils in turmeric, which are dominated by turmerone (35.16%), ar-turmerone (25.20%), curlon (18.21%), and ar-curcumin (3.74%). Turmeric water obtained through juice has the potential as an antibacterial agent. This study is a pure experiment using a post-test-only control group design by examining the effect of turmeric juice (Curcuma domestica Val.) as an antibacterial of Escherichia coli bacteria. The results showed the ability of turmeric juice to inhibit the growth of Escherichia coli bacteria. The concentration of turmeric juice was able to produce an inhibition zone at concentrations ranging from 40% at 14 mm and the highest concentration at 100% at 24 mm. The results of the One Way Anova test showed that the results were not significant because the p-value>0.05 (p-value=0.351). This means that the average diameter of the inhibition at the concentration of turmeric juice 40%, 55%, 70%, 85%, and 100% did not have a significant difference. Turmeric juice has effectiveness in inhibiting the growth of E.coli bacteria.

Keywords

• antibacteri
• inhibitory effect
• tumeric water.