Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats

Amy J. Schuh; Brian R. Amman; Megan E. B. Jones; Tara K. Sealy; Luke S. Uebelhoer; Jessica R. Spengler; Brock E. Martin; Jo Ann D. Coleman-McCray; Stuart T. Nichol; Jonathan S. Towner

doi:10.1038/ncomms14446

Nature Communications (Feb 2017)

Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats

Amy J. Schuh,
Brian R. Amman,
Megan E. B. Jones,
Tara K. Sealy,
Luke S. Uebelhoer,
Jessica R. Spengler,
Brock E. Martin,
Jo Ann D. Coleman-McCray,
Stuart T. Nichol,
Jonathan S. Towner

Affiliations

Amy J. Schuh: Division of High-Consequence Pathogens and Pathology, Viral Special Pathogens Branch, Centers for Disease Control and Prevention
Brian R. Amman: Division of High-Consequence Pathogens and Pathology, Viral Special Pathogens Branch, Centers for Disease Control and Prevention
Megan E. B. Jones: Division of High-Consequence Pathogens and Pathology, Viral Special Pathogens Branch, Centers for Disease Control and Prevention
Tara K. Sealy: Division of High-Consequence Pathogens and Pathology, Viral Special Pathogens Branch, Centers for Disease Control and Prevention
Luke S. Uebelhoer: Division of High-Consequence Pathogens and Pathology, Viral Special Pathogens Branch, Centers for Disease Control and Prevention
Jessica R. Spengler: Division of High-Consequence Pathogens and Pathology, Viral Special Pathogens Branch, Centers for Disease Control and Prevention
Brock E. Martin: Division of High-Consequence Pathogens and Pathology, Viral Special Pathogens Branch, Centers for Disease Control and Prevention
Jo Ann D. Coleman-McCray: Division of High-Consequence Pathogens and Pathology, Viral Special Pathogens Branch, Centers for Disease Control and Prevention
Stuart T. Nichol: Division of High-Consequence Pathogens and Pathology, Viral Special Pathogens Branch, Centers for Disease Control and Prevention
Jonathan S. Towner: Division of High-Consequence Pathogens and Pathology, Viral Special Pathogens Branch, Centers for Disease Control and Prevention

DOI: https://doi.org/10.1038/ncomms14446
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 10

Abstract

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Bats are natural hosts for Marburg virus (MARV), but the mechanism of bat-to-bat transmission is unclear. Here, Schuhet al. monitor MARV infection in a cohort of 38 bats over nine months, find ‘supershedders’ and show that MARV can horizontally transmit between bats.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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