Evaluation of Sleep Quality in Patients with Genital and Nongenital Cutaneous Warts: A prospective controlled study

Abstract

Introduction: Diseases affect sleep quality and the state of sleep quality may also affect the state of diseases by affecting the immune system. Depending on the immune status of the patients with cutaneous warts, the extent of the disease and the response to treatment may vary. Objectives: We aim characterize the association between cutaneous warts and sleep quality. Methods: A prospective controlled study was conducted. Patients over 18 years old with cutaneous wart were enrolled. Control subjects were age- and sex- matched healthy people. Demographic and clinical data of the participants were questioned. Sleep quality of participants was evaluated with Pitssburgh Sleep Quality Index (PSQI). Results: A total of 138 patients with cutaneous warts (genital (n=59), nongenital (n=79)) and 83 controls were interviewed. Patients with cutaneous warts showed significantly higher global PSQI score than the control group (warts vs control, 7.68±3.53 vs 4.92±2.91). The rate of having poor sleep quality in the patient group was higher than the individuals in the control group (Odds ratio (OR): 3.835). Patients with genital warts showed significantly higher global PSQI score than the patients with nongenital warts (genital vs nongenital, 8.61±3.63 vs 6.98±3.32). Female patients with genital warts showed significantly higher global PSQI score than male patients with genital warts. Conclusions: Evaluation of sleep quality in patients with warts, especially in patients with genital warts may be suggested. The management of sleep disturbances in cutaneous warts may help increase the quality of life of patients and may effect on disease control.

Keywords

• warts, sleep quality, Pitssburgh Sleep Quality Index (PSQI)