Insight into the Burden of Malignant Respiratory Tumors and their Relationship with Smoking Rates and Lead Contamination in Mexico
Oliver Mendoza-Cano,
Efrén Murillo-Zamora,
Ángeles Catalina Ochoa-Martínez,
Valeria Argentina Mendoza-Olivo,
Mónica Ríos-Silva,
Xóchitl Trujillo,
Miguel Huerta,
Jaime Alberto Bricio-Barrios,
Verónica Benites-Godínez,
Irma González-Curiel,
Rebeca Yasmín Pérez-Rodríguez,
Nadia Azenet Pelallo-Martínez,
Agustín Lugo-Radillo
Affiliations
Oliver Mendoza-Cano
Facultad de Ingeniería Civil, Universidad de Colima, km. 9 Carretera Colima-Coquimatlán, Coquimatlán C.P. 28400, Colima, Mexico
Efrén Murillo-Zamora
Departamento de Epidemiología, Unidad de Medicina Familiar No. 19, Instituto Mexicano del Seguro Social, Av. Javier Mina 301, Col. Centro, Colima C.P. 28000, Colima, Mexico
Ángeles Catalina Ochoa-Martínez
Laboratorio de Toxicología Molecular, Centro de Investigación Aplicada en Ambiente y Salud (CIAAS), Coordinación Para La Innovación y Aplicación de La Ciencia y La Tecnología (CIACyT), Universidad Autónoma de San Luis Potosí, Av. Sierra Leona 550, Col. Lomas Segunda Sección, San Luis Potosí C.P. 78210, San Luis Potosí, Mexico
Valeria Argentina Mendoza-Olivo
Facultad de Ciencias Químicas, Universidad de Colima, km. 9 Carretera Colima-Coquimatlán, Coquimatlán C.P. 28400, Colima, Mexico
Mónica Ríos-Silva
Centro Universitario de Investigaciones Biomédicas, Universidad de Colima—CONACyT, Av. 25 de Julio 965, Col. Villas San Sebastián, Colima C.P. 28045, Colima, Mexico
Xóchitl Trujillo
Centro Universitario de Investigaciones Biomédicas, Universidad de Colima, Av. 25 de Julio 965, Col. Villas San Sebastián, Colima C.P. 28045, Colima, Mexico
Miguel Huerta
Centro Universitario de Investigaciones Biomédicas, Universidad de Colima, Av. 25 de Julio 965, Col. Villas San Sebastián, Colima C.P. 28045, Colima, Mexico
Jaime Alberto Bricio-Barrios
Facultad de Medicina, Universidad de Colima, Av. Universidad 333, Col. Las Víboras, Colima C.P. 28040, Colima, Mexico
Verónica Benites-Godínez
Coordinación de Educación en Salud, Instituto Mexicano del Seguro Social, Calzada del Ejercito Nacional 14, Col. Fray Junípero Serra, Tepic C.P. 63160, Nayarit, Mexico
Irma González-Curiel
Unidad Académica de Ciencias Químicas, Universidad Autónoma de Zacatecas, Campus UAZ, Siglo XXI. Carr. Zacatecas-Guadalajara Km. 6., Zacatecas C.P. 98160, Zacatecas, Mexico
Rebeca Yasmín Pérez-Rodríguez
Department of Chemistry, DCNE, University of Guanajuato, Campus Guanajuato, Guanajuato C.P. 36700, Guanajuato, Mexico
Nadia Azenet Pelallo-Martínez
Facultad de Ingeniería Civil, Universidad de Colima, km. 9 Carretera Colima-Coquimatlán, Coquimatlán C.P. 28400, Colima, Mexico
Agustín Lugo-Radillo
CONACYT—Faculty of Medicine and Surgery, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca C.P. 68020, Oaxaca, Mexico
We aimed to report the results from the Global Burden of Disease Study 2019 related to respiratory malignant tumors (tracheal, bronchial, and lung) in Mexico. We also evaluated the relationship between the burden of these neoplasms and the proportion of daily smokers and total lead emissions in 2019. A cross-sectional analysis of ecological data was performed. The burden of these tumors was 152,189 disability-adjusted life-years (DALYs), and years of life lost (YLL) contributed to 99% of them. The highest DALYs rates (per 100,000) were observed in the states of Sinaloa, Chihuahua, Baja California Sur, Sonora, and Nayarit. We documented a linear relationship between the DALYs rates and the prevalence of daily smokers (β = 8.50, 95% CI 1.58–15.38) and the total lead emissions (tons/year: β = 4.04, 95% CI 0.07–8.01). If later replicated, our study would provide insight into the major relevance of regulating tobacco use and the activities associated with the production of lead dust and other hazardous contaminants.
