Assessment of viral load in patients with HPV-associated cervicitis during the course of complex treatment

Abstract

The article presents information about examination and treatment of the 39 women with chronic cervicitis associated with papillomavirus infection (HPV). Inosine pranobex is a drug with immunostimulating and anti-inflammatory action. It was used in the complex treatment of the patients. Patients were given 3 courses of inosine pranobex in a daily dose of 3000 mg with an interval of 10 days. Efficacy of the therapy was evaluated on the basis of clinical data, PAP-test, colposcopy, PCR - determination of HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 types, as well as viral load of HPV before and after treatment. In 41.03±7.88% of patients who had a cytological picture of ASCUS, LSIL, HSIL, the concentration of HPV was clinically significant. Among the different types of HPV with high oncological risk, HPV types 16 and associations of different types of HPV prevailed in patients (p

Keywords

• chronic cervicitis
• human papillomavirus
• viral load
• inosine pranobex