CO2 fixation by anaerobic non-photosynthetic mixotrophy for improved carbon conversion

Shawn W. Jones; Alan G. Fast; Ellinor D. Carlson; Carrissa A. Wiedel; Jennifer Au; Maciek R. Antoniewicz; Eleftherios T. Papoutsakis; Bryan P. Tracy

doi:10.1038/ncomms12800

Nature Communications (Sep 2016)

CO2 fixation by anaerobic non-photosynthetic mixotrophy for improved carbon conversion

Shawn W. Jones,
Alan G. Fast,
Ellinor D. Carlson,
Carrissa A. Wiedel,
Jennifer Au,
Maciek R. Antoniewicz,
Eleftherios T. Papoutsakis,
Bryan P. Tracy

Affiliations

Shawn W. Jones: White Dog Labs, Inc.
Alan G. Fast: Department of Chemical and Biomolecular Engineering and the Delaware Biotechnology Institute, University of Delaware
Ellinor D. Carlson: Department of Chemical and Biomolecular Engineering and the Delaware Biotechnology Institute, University of Delaware
Carrissa A. Wiedel: White Dog Labs, Inc.
Jennifer Au: Department of Chemical and Biomolecular Engineering and Metabolic Engineering and Systems Biology Laboratory, University of Delaware
Maciek R. Antoniewicz: Department of Chemical and Biomolecular Engineering and Metabolic Engineering and Systems Biology Laboratory, University of Delaware
Eleftherios T. Papoutsakis: Department of Chemical and Biomolecular Engineering and the Delaware Biotechnology Institute, University of Delaware
Bryan P. Tracy: White Dog Labs, Inc.

DOI: https://doi.org/10.1038/ncomms12800
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 9

Abstract

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Microbial fermentation yield is limited by CO2 loss in glycolysis. Here, the authors engineered Clostridium ljungdahlii for the anaerobic, non-photosynthetic mixotrophy production of acetone, increasing carbon product yield while reducing CO2emissions from a biogenic feedstock fermentation.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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