Transplantation Direct (2017-08-01)

Renal Autotransplantation and Extracorporeal Nephron-Sparing Surgery for De Novo Renal Cell Carcinoma in a Kidney Allograft

  • Shinichiro Ono, MD, PhD,
  • Takashi Kenmochi, MD, PhD,
  • Taihei Ito, MD, PhD,
  • Naohiro Aida, MD,
  • Kazunori Otsuki, MD, PhD,
  • Naotake Akutsu, MD, PhD,
  • Michihiro Maruyama, MD, PhD,
  • Mamoru Kusaka, MD, PhD,
  • Ryoichi Shiroki, MD, PhD,
  • Kiyotaka Hoshinaga, MD, PhD

DOI
https://doi.org/10.1097/TXD.0000000000000714
Journal volume & issue
Vol. 3, no. 8
p. e122

Abstract

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Abstract. De novo renal cell carcinoma (RCC) rarely occurs in kidney allografts; however, the risk of RCC in these patients is 100-fold that of the general healthy population. Although total nephrectomy has been the standard treatment for kidney allograft RCC, several authors have reported that early-stage RCC in kidney allografts was successfully treated with nephron-sparing surgery. We herein describe a new procedure involving renal autotransplantation and extracorporeal nephron-sparing surgery, which was performed to treat de novo RCC near the hilum of a transplanted kidney. In the 22 months since transplantation, the patient's renal function has been favorable, and no recurrence has been observed. In conclusion, renal autotransplantation is a feasible technique for the treatment of RCC in kidney allografts, especially RCC located near the hilum.