Renal Autotransplantation and Extracorporeal Nephron-Sparing Surgery for De Novo Renal Cell Carcinoma in a Kidney Allograft

Shinichiro Ono, MD, PhD; Takashi Kenmochi, MD, PhD; Taihei Ito, MD, PhD; Naohiro Aida, MD; Kazunori Otsuki, MD, PhD; Naotake Akutsu, MD, PhD; Michihiro Maruyama, MD, PhD; Mamoru Kusaka, MD, PhD; Ryoichi Shiroki, MD, PhD; Kiyotaka Hoshinaga, MD, PhD

doi:10.1097/TXD.0000000000000714

Transplantation Direct (Aug 2017)

Renal Autotransplantation and Extracorporeal Nephron-Sparing Surgery for De Novo Renal Cell Carcinoma in a Kidney Allograft

Shinichiro Ono, MD, PhD,
Takashi Kenmochi, MD, PhD,
Taihei Ito, MD, PhD,
Naohiro Aida, MD,
Kazunori Otsuki, MD, PhD,
Naotake Akutsu, MD, PhD,
Michihiro Maruyama, MD, PhD,
Mamoru Kusaka, MD, PhD,
Ryoichi Shiroki, MD, PhD,
Kiyotaka Hoshinaga, MD, PhD

Affiliations

Shinichiro Ono, MD, PhD: 1 Department of Organ Transplant Surgery, Fujita Health University, School of Medicine, Aichi, Japan.
Takashi Kenmochi, MD, PhD: 1 Department of Organ Transplant Surgery, Fujita Health University, School of Medicine, Aichi, Japan.
Taihei Ito, MD, PhD: 1 Department of Organ Transplant Surgery, Fujita Health University, School of Medicine, Aichi, Japan.
Naohiro Aida, MD: 1 Department of Organ Transplant Surgery, Fujita Health University, School of Medicine, Aichi, Japan.
Kazunori Otsuki, MD, PhD: 2 Department of Surgery, Chiba-East National Hospital, Chiba, Japan.
Naotake Akutsu, MD, PhD: 2 Department of Surgery, Chiba-East National Hospital, Chiba, Japan.
Michihiro Maruyama, MD, PhD: 2 Department of Surgery, Chiba-East National Hospital, Chiba, Japan.
Mamoru Kusaka, MD, PhD: 3 Department of Urology, Fujita Health University, School of Medicine, Aichi, Japan.
Ryoichi Shiroki, MD, PhD: 3 Department of Urology, Fujita Health University, School of Medicine, Aichi, Japan.
Kiyotaka Hoshinaga, MD, PhD: 3 Department of Urology, Fujita Health University, School of Medicine, Aichi, Japan.

DOI: https://doi.org/10.1097/TXD.0000000000000714
Journal volume & issue: Vol. 3, no. 8
p. e122

Abstract

Read online

Abstract. De novo renal cell carcinoma (RCC) rarely occurs in kidney allografts; however, the risk of RCC in these patients is 100-fold that of the general healthy population. Although total nephrectomy has been the standard treatment for kidney allograft RCC, several authors have reported that early-stage RCC in kidney allografts was successfully treated with nephron-sparing surgery. We herein describe a new procedure involving renal autotransplantation and extracorporeal nephron-sparing surgery, which was performed to treat de novo RCC near the hilum of a transplanted kidney. In the 22 months since transplantation, the patient's renal function has been favorable, and no recurrence has been observed. In conclusion, renal autotransplantation is a feasible technique for the treatment of RCC in kidney allografts, especially RCC located near the hilum.

Published in Transplantation Direct

ISSN: 2373-8731 (Online)
Publisher: Wolters Kluwer
Country of publisher: United States
LCC subjects: Medicine: Surgery
Website: http://journals.lww.com/transplantationdirect/Pages/default.aspx

About the journal