Nature Communications (May 2017)
Induction of resident memory T cells enhances the efficacy of cancer vaccine
- Mevyn Nizard,
- Hélène Roussel,
- Mariana O. Diniz,
- Soumaya Karaki,
- Thi Tran,
- Thibault Voron,
- Estelle Dransart,
- Federico Sandoval,
- Marc Riquet,
- Bastien Rance,
- Elie Marcheteau,
- Elizabeth Fabre,
- Marion Mandavit,
- Magali Terme,
- Charlotte Blanc,
- Jean-Baptiste Escudie,
- Laure Gibault,
- Françoise Le Pimpec Barthes,
- Clemence Granier,
- Luis C. S. Ferreira,
- Cecile Badoual,
- Ludger Johannes,
- Eric Tartour
Affiliations
- Mevyn Nizard
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Hélène Roussel
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Mariana O. Diniz
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Soumaya Karaki
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Thi Tran
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Thibault Voron
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Estelle Dransart
- Institut Curie, PSL Research University, Chemical Biology of Membranes and Therapeutic Delivery Unit
- Federico Sandoval
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Marc Riquet
- Hopital Europeen Georges Pompidou, Chrirurgie Thoracique Générale, Oncologique et Transplantation
- Bastien Rance
- Department of Medical Bioinformatics, Hopital Européen Georges Pompidou
- Elie Marcheteau
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Elizabeth Fabre
- Departement of Medical Oncology, Hopital Européen Georges Pompidou
- Marion Mandavit
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Magali Terme
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Charlotte Blanc
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Jean-Baptiste Escudie
- Department of Medical Bioinformatics, Hopital Européen Georges Pompidou
- Laure Gibault
- Department of Pathology, Hopital Européen Georges Pompidou
- Françoise Le Pimpec Barthes
- Hopital Europeen Georges Pompidou, Chrirurgie Thoracique Générale, Oncologique et Transplantation
- Clemence Granier
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Luis C. S. Ferreira
- Institute of Biomedical Sciences, University of Sao Paulo, Av Prof Lineu Prestes
- Cecile Badoual
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- Ludger Johannes
- Institut Curie, PSL Research University, Chemical Biology of Membranes and Therapeutic Delivery Unit
- Eric Tartour
- INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité
- DOI
- https://doi.org/10.1038/ncomms15221
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 11
Abstract
Resident memory T cells (Trm) are memory T cells that remain in tissue. Here, the authors show that induction of Trm cells is required for control of tumour growth following mucosal vaccination in mice bearing head and neck cancer and that Trm cells in human lung cancer correlates with a better survival.
