240 Presentation of DLL4 and VCAM on paramagnetic beads replicates thymic Notch signaling and enables differentiation of functional of iPSC derived TCR T-cells in vitro

• Chris Bond,
• Valerie Wall,
• Siddarth Chandrasekaran,
• Melanie Kardel,
• Elisa Martinez,
• Nabil Zeidan,
• Avisek Deyati,
• Dylan Lee,
• Negin Farahani,
• Amanda AuYeung,
• Omar Subedar,
• Michael Cadell,
• Sommer Apelu,
• Laura Prochazka,
• Zahra Sahaf,
• Angela Duong,
• Cole Zmurchok,
• Boyoung Yoon,
• Dan Kirouac,
• Muluken Belew,
• Jasdeep Mann,
• Deepika Rajesh

Affiliations

Chris Bond

3Department of Emergency Medicine, University of Calgary, Calgary, Alberta, Canada

Valerie Wall

OncResponse Inc., Seattle, WA, USA

Siddarth Chandrasekaran

1Notch Therapeutics, Vancouver, BC, Canada

Melanie Kardel

1Notch Therapeutics, Vancouver, BC, Canada

Elisa Martinez

1Notch Therapeutics, Vancouver, BC, Canada

Nabil Zeidan

2Notch Therapeutics, Toronto, ON, Canada

Avisek Deyati

1Notch Therapeutics, Vancouver, BC, Canada

Dylan Lee

2Notch Therapeutics, Toronto, ON, Canada

Negin Farahani

1Notch Therapeutics, Vancouver, BC, Canada

Amanda AuYeung

2Notch Therapeutics, Toronto, ON, Canada

Omar Subedar

2Notch Therapeutics, Toronto, ON, Canada

Michael Cadell

3Notch Therapeutics, Seattle, WA, USA

Sommer Apelu

3Notch Therapeutics, Seattle, WA, USA

Laura Prochazka

3Notch Therapeutics, Seattle, WA, USA

Zahra Sahaf

2Notch Therapeutics, Toronto, ON, Canada

Angela Duong

1Notch Therapeutics, Vancouver, BC, Canada

Cole Zmurchok

1Notch Therapeutics, Vancouver, BC, Canada

Boyoung Yoon

1Notch Therapeutics, Vancouver, BC, Canada

Dan Kirouac

3Notch Therapeutics, Seattle, WA, USA

Muluken Belew

2Notch Therapeutics, Toronto, ON, Canada

Jasdeep Mann

3Notch Therapeutics, Seattle, WA, USA

Deepika Rajesh

3Notch Therapeutics, Seattle, WA, USA