Microfluidic devices for light stimulation of cell suspensions: experimental analysis of the flow behaviour using a micro-PIV system

Abstract

Photobiomodulation, the light stimulation of regenerative active cells, offers great potential for promoting tissue repair and regeneration. In this study, we show the design and fabrication of two microchannel devices for light stimulation of cell suspensions. The microchannels in the 3D-printed devices allow the uniform distribution of cells and exposure to light. Our experimental results demonstrate the ability of these microfluidic devices to improve light intake of cells in suspensions during photobiomodulation, thus enhancing the therapeutic potential.

Keywords

• microfluidic device
• light stimulation
• cell suspension
• 3d-printing
• micro-piv