High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment

• Susan L. Heatley,
• Teresa Sadras,
• Chung H. Kok,
• Eva Nievergall,
• Kelly Quek,
• Phuong Dang,
• Barbara McClure,
• Nicola Venn,
• Sarah Moore,
• Jeffrey Suttle,
• Tamara Law,
• Anthea Ng,
• Walter Muskovic,
• Murray D. Norris,
• Tamas Revesz,
• Michael Osborn,
• Andrew S. Moore,
• Ram Suppiah,
• Chris Fraser,
• Frank Alvaro,
• Timothy P. Hughes,
• Charles G. Mullighan,
• Glenn M. Marshall,
• Luciano Dalla Pozza,
• David T. Yeung,
• Rosemary Sutton,
• Deborah L. White

Affiliations

Susan L. Heatley

Cancer Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia;Discipline of Medicine, University of Adelaide, SA, Australia;Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG), Australia

Teresa Sadras

Cancer Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia;Discipline of Medicine, University of Adelaide, SA, Australia

Chung H. Kok

Cancer Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia;Discipline of Medicine, University of Adelaide, SA, Australia

Eva Nievergall

Cancer Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia;Discipline of Medicine, University of Adelaide, SA, Australia

Kelly Quek

Cancer Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia

Phuong Dang

Cancer Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia

Barbara McClure

Cancer Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia

Nicola Venn

Molecular Diagnostics, Children’s Cancer Institute, Sydney, NSW, Australia

Sarah Moore

Genetics and Molecular Pathology, SA Pathology, Adelaide, SA, Australia

Jeffrey Suttle

Genetics and Molecular Pathology, SA Pathology, Adelaide, SA, Australia

Tamara Law

Molecular Diagnostics, Children’s Cancer Institute, Sydney, NSW, Australia

Anthea Ng

Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG), Australia;Sydney Children’s Hospital Network, Sydney, NSW, Australia

Walter Muskovic

Molecular Diagnostics, Children’s Cancer Institute, Sydney, NSW, Australia

Murray D. Norris

Molecular Diagnostics, Children’s Cancer Institute, Sydney, NSW, Australia

Tamas Revesz

Discipline of Medicine, University of Adelaide, SA, Australia;Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG), Australia;Women’s & Children’s Hospital, Adelaide, SA, Australia

Michael Osborn

Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG), Australia;Women’s & Children’s Hospital, Adelaide, SA, Australia;Australian Genomic Health Alliance (AGHA), Australia

Andrew S. Moore

Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG), Australia;Oncology Services Group, Children’s Health Queensland Hospital and Health Service, Brisbane, QLD, Australia;The University of Queensland Diamantina Institute and UQ Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia

Ram Suppiah

Mater Children’s Hospital Brisbane, QLD, Australia

Chris Fraser

Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG), Australia;Oncology Services Group, Children’s Health Queensland Hospital and Health Service, Brisbane, QLD, Australia

Frank Alvaro

Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG), Australia;John Hunter Children’s Hospital, Newcastle, NSW, Australia

Timothy P. Hughes

Cancer Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia;Discipline of Medicine, University of Adelaide, SA, Australia;Division of Haematology, SA Pathology, Adelaide, SA, Australia

Charles G. Mullighan

Department of Pathology, St Jude Children’s Research Hospital, Memphis, TN, USA

Glenn M. Marshall

Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG), Australia;Molecular Diagnostics, Children’s Cancer Institute, Sydney, NSW, Australia;Sydney Children’s Hospital Network, Sydney, NSW, Australia;Australian Genomic Health Alliance (AGHA), Australia;School of Women and Children’s Health, University of New South Wales, Sydney, NSW, Australia

Luciano Dalla Pozza

Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG), Australia;Sydney Children’s Hospital Network, Sydney, NSW, Australia

David T. Yeung

Cancer Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia;Discipline of Medicine, University of Adelaide, SA, Australia;Division of Haematology, SA Pathology, Adelaide, SA, Australia

Rosemary Sutton

Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG), Australia;Molecular Diagnostics, Children’s Cancer Institute, Sydney, NSW, Australia;Australian Genomic Health Alliance (AGHA), Australia;School of Women and Children’s Health, University of New South Wales, Sydney, NSW, Australia

Deborah L. White

Cancer Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia;Discipline of Medicine, University of Adelaide, SA, Australia;Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG), Australia;Australian Genomic Health Alliance (AGHA), Australia;Discipline of Paediatrics, University of Adelaide, SA, Australia