The importance of methionine metabolism

Ramon I Klein Geltink; Erika L Pearce

doi:10.7554/eLife.47221

eLife (May 2019)

The importance of methionine metabolism

Ramon I Klein Geltink,
Erika L Pearce

Affiliations

Ramon I Klein Geltink: ORCiD; Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany
Erika L Pearce: ORCiD; Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany

DOI: https://doi.org/10.7554/eLife.47221
Journal volume & issue: Vol. 8

Abstract

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T helper cells import the amino acid methionine to synthesize new proteins and to provide the methyl groups needed for the methylation of RNA and DNA that drives T cell proliferation and differentiation.

Published in eLife

ISSN: 2050-084X (Online)
Publisher: eLife Sciences Publications Ltd
Country of publisher: United Kingdom
LCC subjects: Medicine; Science: Biology (General)
Website: https://elifesciences.org

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Abstract

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