Three bisabolane sesquiterpenoids and a phenolic derivative from the fungus Stereum hirsutum

Abstract

Objective: To explore the secondary metabolites of the higher fungus Stereum hirsutum. Methods: The structures of these compounds were elucidated by extensive spectroscopic analyses and NMR calculations. Results: Three new bisabolane sesquiterpenoids, sterene acids A–C (1–3), and one new phenolic derivative, sterephenol A (4), were isolated from the higher fungus S. hirsutum. Conclusion: Compound 1 is the first example of bisabolane sesquiterpenoid bearing an allene group. It is also the first time to discover bisabolane sesquiterpenoids from the fungus S. hirsutum.

Keywords

• Stereum hirsutum
• Sesquiterpenoids
• Phenolic derivative