Nature Communications (Feb 2022)

Genome binning of viral entities from bulk metagenomics data

  • Joachim Johansen,
  • Damian R. Plichta,
  • Jakob Nybo Nissen,
  • Marie Louise Jespersen,
  • Shiraz A. Shah,
  • Ling Deng,
  • Jakob Stokholm,
  • Hans Bisgaard,
  • Dennis Sandris Nielsen,
  • Søren J. Sørensen,
  • Simon Rasmussen

DOI
https://doi.org/10.1038/s41467-022-28581-5
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 12

Abstract

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Here, Johansen et al. develop an approach, Phages from Metagenomics Binning (PHAMB), that allows the binning of thousands of viral genomes directly from bulk metagenomics data, while simultaneously enabling clustering of viral genomes into accurate taxonomic viral populations, unveiling viral-microbial host interactions in the gut.