Nature Communications (Feb 2023)
Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes
- Taniya Bhardwaj,
- Kundlik Gadhave,
- Shivani K. Kapuganti,
- Prateek Kumar,
- Zacharias Faidon Brotzakis,
- Kumar Udit Saumya,
- Namyashree Nayak,
- Ankur Kumar,
- Richa Joshi,
- Bodhidipra Mukherjee,
- Aparna Bhardwaj,
- Krishan Gopal Thakur,
- Neha Garg,
- Michele Vendruscolo,
- Rajanish Giri
Affiliations
- Taniya Bhardwaj
- School of Biosciences and Bioengineering, Indian Institute of Technology Mandi
- Kundlik Gadhave
- School of Biosciences and Bioengineering, Indian Institute of Technology Mandi
- Shivani K. Kapuganti
- School of Biosciences and Bioengineering, Indian Institute of Technology Mandi
- Prateek Kumar
- School of Biosciences and Bioengineering, Indian Institute of Technology Mandi
- Zacharias Faidon Brotzakis
- Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge
- Kumar Udit Saumya
- School of Biosciences and Bioengineering, Indian Institute of Technology Mandi
- Namyashree Nayak
- School of Biosciences and Bioengineering, Indian Institute of Technology Mandi
- Ankur Kumar
- School of Biosciences and Bioengineering, Indian Institute of Technology Mandi
- Richa Joshi
- School of Biosciences and Bioengineering, Indian Institute of Technology Mandi
- Bodhidipra Mukherjee
- School of Biosciences and Bioengineering, Indian Institute of Technology Mandi
- Aparna Bhardwaj
- School of Biosciences and Bioengineering, Indian Institute of Technology Mandi
- Krishan Gopal Thakur
- Structural Biology Laboratory, G. N. Ramachandran Protein Centre, CSIR-Institute of Microbial Technology
- Neha Garg
- Department of Medicinal Chemistry, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University
- Michele Vendruscolo
- Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge
- Rajanish Giri
- School of Biosciences and Bioengineering, Indian Institute of Technology Mandi
- DOI
- https://doi.org/10.1038/s41467-023-36234-4
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 16
Abstract
Bhardwaj et al., have explored the proteomes of SARS-CoV and SARS-CoV-2, and have demonstrated the amyloid formation of viral proteins, in vitro, through diverse biophysical techniques.
