Nature Communications (Jan 2023)

DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer

  • Maria Zhivagui,
  • Areebah Hoda,
  • Noelia Valenzuela,
  • Yi-Yu Yeh,
  • Jason Dai,
  • Yudou He,
  • Shuvro P. Nandi,
  • Burcak Otlu,
  • Bennett Van Houten,
  • Ludmil B. Alexandrov

DOI
https://doi.org/10.1038/s41467-023-35876-8
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 14

Abstract

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Nail polish dryers commonly emit ultraviolet A (UVA) light, but the effects of this irradiation on mammalian cells remain unclear. Here, the authors examine the effects of UVA irradiation by a nail polish dryer on the genomes of mammalian cell lines, finding high levels of reactive oxygen species and related mutational signatures.