Communications Biology (Dec 2022)
Bayesian model and selection signature analyses reveal risk factors for canine atopic dermatitis
- Katarina Tengvall,
- Elisabeth Sundström,
- Chao Wang,
- Kerstin Bergvall,
- Ola Wallerman,
- Eric Pederson,
- Åsa Karlsson,
- Naomi D. Harvey,
- Sarah C. Blott,
- Natasha Olby,
- Thierry Olivry,
- Gustaf Brander,
- Jennifer R. S. Meadows,
- Petra Roosje,
- Tosso Leeb,
- Åke Hedhammar,
- Göran Andersson,
- Kerstin Lindblad-Toh
Affiliations
- Katarina Tengvall
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Elisabeth Sundström
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Chao Wang
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Kerstin Bergvall
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
- Ola Wallerman
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Eric Pederson
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Åsa Karlsson
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Naomi D. Harvey
- School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus
- Sarah C. Blott
- School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus
- Natasha Olby
- Department of Clinical Sciences, North Carolina State University
- Thierry Olivry
- Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine
- Gustaf Brander
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Jennifer R. S. Meadows
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Petra Roosje
- Division of Clinical Dermatology, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern
- Tosso Leeb
- Institute of Genetics, Vetsuisse Faculty, University of Bern
- Åke Hedhammar
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
- Göran Andersson
- Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences
- Kerstin Lindblad-Toh
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- DOI
- https://doi.org/10.1038/s42003-022-04279-8
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 17
Abstract
A genome-wide evaluation in four different dog breeds identifies multiple genomic regions that were significantly related to risk of atopic dermatitis, providing additional biological insights into disease pathogenesis in dogs.