Are Mean Platelet Volume and Platelet Count Associated with Presence of Thrombus in Patients with Abdominal Aortic Aneursym?

Abstract

Aim: Mean platelet volume (MPV) is an indicator of platelet activation and is associated with inflammation and thrombus cascade. In this study, we aimed to compare platelet count and MPV levels in patients with infrarenal abdominal aortic aneurysm (IAAA) with and without thrombosis in the aneurysm. Methods: In this cross sectional study, we included 76 consecutive patients who were diagnosed with IAAA. The patients were divided into two groups according to the presence or absence of thrombus in the aneurysm and, clinical and laboratory values were compared. Results: Twenty-seven (35.5%) patients with IAAA had thrombus and 49 (64.5%) did not have thrombus. There was no statistically significant difference in demographic characteristics, symptoms, additional diseases and laboratory findings between the groups. There was also no significant difference in MPV values between patients with and without thrombus in aneurysm (9.30±1.0 vs. 9.84±1.4; p=0.09). Conclusion: There was no difference in platelet count and MPV values between patients with and without thrombus in aneurysm. It may be more appropriate to evaluate a larger number of markers together to identify the prothrombotic state in thrombotic and nonthrombotic IAAA patients.

Keywords

• Aneurysm
• mean platelet volume
• thrombocyte
• thrombus