Gold(I)-catalyzed formation of furans from γ-acyloxyalkynyl ketones

Abstract

Various γ-acyloxyalkynyl ketones were efficiently converted into highly substituted furans with 2.5 mol % of triflimide (triphenylphosphine)gold(I) as a catalyst in dichloroethane at 70 °C.

Keywords

• alkynyl ketones
• cycloisomerization
• furans
• gold-catalysis
• 1,2-migration