Metabolic responses to hyperglycaemia during exercise in elderly men

Abstract

Purpose: The present study was designed to determine the metabolic responses to hyperglycaemia duringexercise in elderly men.Methods: Eight healthy males (Age, 63.3±5.2 years) voluntarily participated and reported to the physiologylaboratory on two separate occasions. With one week intervening subjects performed 40 min exercise on acycle ergometer at 60% VO2max after 30 minutes of ‘prime’ glucose or placebo infusion. Respiratory gaseswere undertaken throughout the exercise and four blood samples were taken before infusion, after 30 mininfusion, after 20 min exercise and immediately after exercise. Blood samples were analyzed to determineinsulin, NEFA, glycerol, 3- OHB and HOMA Scores. Fat and carbohydrate oxidation were calculated by usingrespiratory gases of O2 and CO2.Results: Insulin and glucose concentrations were significantly (p0.05).Conclusions: Based on the findings of the present study it could be concluded that in elderly men themaintenance of blood glucose during exercise through glucose infusion affects on lipolysis and metabolicfactors, but has no effect on muscular fat and carbohydrate oxidation.

Keywords

• cycling: cycling
• fat oxidation
• carbohydrate oxidation
• elderly