Cerebellar dysregulation and heterogeneity of mood disorders

Abstract

Edward H Tobe Department of Psychiatry, Cooper Medical School of Rowan University, Camden, NJ, USA Abstract: This paper discusses diverse studies to consider the hypothesis that cerebellar pathology supports the heterogeneous metabolic pathologies of mood disorders. The evidence presented includes studies selected from the following areas of scientific research: magnetic resonance imaging, histology, clinical syndromes, comparative anatomy, neuronal connections, and mitochondrial dysfunction. The gamut of different scientific study methods confirms the validity of the involvement of the cerebellum in mood disorders. Keywords: psychiatry, neurology, depression, cerebellum, neuropathology, heterogeneity