Brain-wide reconstruction of inhibitory circuits after traumatic brain injury

Jan C. Frankowski; Alexa Tierno; Shreya Pavani; Quincy Cao; David C. Lyon; Robert F. Hunt

doi:10.1038/s41467-022-31072-2

Nature Communications (Jun 2022)

Brain-wide reconstruction of inhibitory circuits after traumatic brain injury

Jan C. Frankowski,
Alexa Tierno,
Shreya Pavani,
Quincy Cao,
David C. Lyon,
Robert F. Hunt

Affiliations

Jan C. Frankowski: Department of Anatomy & Neurobiology, University of California
Alexa Tierno: Department of Anatomy & Neurobiology, University of California
Shreya Pavani: Department of Anatomy & Neurobiology, University of California
Quincy Cao: Department of Anatomy & Neurobiology, University of California
David C. Lyon: Department of Anatomy & Neurobiology, University of California
Robert F. Hunt: Department of Anatomy & Neurobiology, University of California

DOI: https://doi.org/10.1038/s41467-022-31072-2
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 16

Abstract

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Traumatic brain injury is often followed by changes in neural connectivity. This study describes how inputs to a population of inhibitory neurons change to favor local over long-range connectivity in a mouse model of traumatic brain injury.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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