Dietary polyphenols enhance optogenetic recall of fear memory in hippocampal dentate gyrus granule neuron subpopulations

Abstract

Chad Smith et al. show that dietary polyphenols, compounds found in grapes, enable mice to remember fearful events more effectively and map this function to the hippocampal dentate gyrus neurons. This study offers a way to identify the cellular subpopulations regulated by dietary polyphenols.