Evaluation of total antioxidant level of saliva in modulation of caries occurrence and progression in children

Abstract

Context: Recent studies have implicated a direct relation between dental caries and salivary total antioxidant level (TAL), which can be suggested as an indicator (either harmful or protective) for susceptibility of individuals for dental caries. Aim: To evaluate the total antioxidant level (TAL) in unstimulated saliva of children, and to correlate the TAL with caries experience and BMI (body mass index). Settings and Design: 60 children, aged 6-12 yrs, were randomly selected for the study. Two groups were made (study group n=30 and control group n=30), and subdivisions based on gender were made out of both groups [male (n=15) and female (n=15)]. In control group, subjects with no dental caries and study group, subjects having decayed teeth score ≥4 were included. Statistical Analysis: Data analysis was done using Statistical Package for Social Sciences (SPSS V. 21). Shapiro – Wilks test showed that TAL (absorbance) did not follow normal distribution. Hence, for comparison between cases and control for TAL non-parametric test namely Mann- Whitney U test was applied. Results: Statistically significant strong positive correlation was seen between age and TAL (P< 0.05).

Keywords

• Body mass index
• dental caries
• oxidative stress
• total antioxidant level