Salmonella Subtypes with Increased MICs for Azithromycin in Travelers Returned to the Netherlands

Abstract

Antimicrobial susceptibility was analyzed for 354 typhoidal Salmonella isolates collected during 1999–2012 in the Netherlands. In 16.1% of all isolates and in 23.8% of all isolates that showed increased MICs for ciprofloxacin, the MIC for azithromycin was increased. This resistance may complicate empirical treatment of enteric fever.

Keywords

• enteric fever
• azithromycin
• drug resistance
• travel medicine
• Salmonella
• typhi