Frontiers in Pharmacology (Dec 2023)

Psoriasis comorbid with atherosclerosis meets in lipid metabolism

  • Liuping Chen,
  • Huiqi Chen,
  • Huiqi Chen,
  • Sien Guo,
  • Sien Guo,
  • Zhijun Chen,
  • Zhijun Chen,
  • Haifeng Yang,
  • Yanjiao Liu,
  • Xiaoling Chen,
  • Xinming Chen,
  • Tingting Du,
  • Xinyao Long,
  • Jiaxiong Zhao,
  • Jiaxiong Zhao,
  • Mingli Guo,
  • Tianfeng Lao,
  • DongHui Huang,
  • Lei Wang,
  • Lei Wang,
  • Jing Chen,
  • Chunping Liu,
  • Chunping Liu,
  • Chunping Liu,
  • Chunping Liu

DOI
https://doi.org/10.3389/fphar.2023.1308965
Journal volume & issue
Vol. 14

Abstract

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Psoriasis (PSO) is a common skin disease affecting approximately 1%–3% of the population, and the incidence rate is increasing yearly. PSO is associated with a dramatically increased risk of cardiovascular disease, the most common of which is atherosclerosis (AS). In the past, inflammation was considered to be the triggering factor of the two comorbidities, but in recent years, studies have found that lipid metabolism disorders increase the probability of atherosclerosis in patients with psoriasis. In this review, we discuss epidemiological studies, clinical treatment methods, risk factors, and lipid metabolism of psoriasis and atherosclerosis comorbidities.

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