Nature Communications (Jan 2017)

Environmental stresses induce transgenerationally inheritable survival advantages via germline-to-soma communication in Caenorhabditis elegans

  • Saya Kishimoto,
  • Masaharu Uno,
  • Emiko Okabe,
  • Masanori Nono,
  • Eisuke Nishida

DOI
https://doi.org/10.1038/ncomms14031
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 12

Abstract

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Environmental stress causes epigenetic changes but it is unclear if such changes are transgenerational. Here, the authors show that inC. elegans, increased resistance to oxidative stress and proteotoxicity in the parental generation and linked epigenetic changes are transmitted to subsequent generations.