Case Reports in Medicine (Jan 2012)

A Case of Acute Prosthesis Migration after Femoral Head Replacement due to Osteomalacia by FGF23-Induced Tumor

  • Shinya Hayashi,
  • Takayuki Nishiyama,
  • Takaaki Fujishiro,
  • Shingo Hashimoto,
  • Noriyuki Kanzaki,
  • Teruya Kawamoto,
  • Toshihiro Akisue,
  • Kotaro Nishida,
  • Masahiro Kurosaka

DOI
https://doi.org/10.1155/2012/503956
Journal volume & issue
Vol. 2012

Abstract

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Fibroblast growth factor 23 (FGF23) was recently identified as an important factor involved in the development of hypophosphatemic rickets and osteomalacia. We experienced a rare case of acute prosthesis migration after hemihip arthroplasty due to FGF23-induced tumor. The patient underwent femoral head replacement because of femoral neck fracture, but prosthesis migration was occurred at 1 week after operation. The patient took various examinations, and FGF23-induced tumor was found in his right wrist. The tumor was resected, and he underwent total hip arthroplasty 8 month later. Finally, he was able to obtain free gait without pain.