S191: CALRETICULIN-MUTATED HEMATOPOIETIC CELLS ARE VULNERABLE TO THE COMBINED INHIBITION OF THE PROTEASOME AND THE IRE1A-XBP1 AXIS OF THE UNFOLDED PROTEIN RESPONSE
J. S. Jutzi,
A. E. Marneth,
M. J. Jimenez-Santos,
A. Guerra-Moreno,
S. A. Myers,
S. A. Carr,
P. van Galen,
F. Al-Shahrour,
A. S. Nam,
A. Mullally
Affiliations
J. S. Jutzi
1 Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, United States of America
A. E. Marneth
1 Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, United States of America
M. J. Jimenez-Santos
2 Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
A. Guerra-Moreno
1 Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, United States of America
S. A. Myers
3 The Broad Institute of MIT and Harvard, Cambridge
S. A. Carr
3 The Broad Institute of MIT and Harvard, Cambridge
P. van Galen
1 Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, United States of America
F. Al-Shahrour
5 Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid
A. S. Nam
6 Weill Cornell Medicine, New York, United States of America
A. Mullally
1 Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, United States of America
